Results 151 to 160 of about 62,890,502 (300)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Titanosaur eggshells from the latest Cretaceous of Patagonia, Argentina: implications for nesting at high latitude. [PDF]

R Soc Open Sci
Tanaka K, Novas FE, Manabe M, Sakata C, Garcia Marsà JA, Zelenitsky DK.   +5 more
europepmc   +1 more source

Elaborer un plan de recrutement et de formation pour les animateurs périscolaires

, 2014
Cet article trouve son origine dans la journée d'étude "Aménagement des rythmes scolaires et animation" organisée par le département Carrières Sociales de l'I.U.T. de Nice en mars 2014 à Menton Soucieux des nécessités réglementaires, des besoins de fonctionnement et des difficultés pour recruter des personnels qualifiés, l'article propose une ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Französisch vor Englisch

Babylonia
En prenant comme point de départ la situation linguistique en Europe, cette contribution se propose de montrer comment sera organisée dans le cadre du projet Passepartout en Suisse alémanique la mise en place d’un enseignement du français langue ...
Christine Le Pape Racine
doaj  

Implementation intentions as an acceptable health behaviour change strategy? Insights from people with lower socio-economic position in think-aloud interviews. [PDF]

Br J Health Psychol
van den Bekerom L, van Gestel LC, Koivusaari S, Bussemaker J, Adriaanse MA.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Etude en ligne : Plan de formation dans les entreprises, de la formalité à l’outil stratégique

, 2013
SEILER Carine (dir.). Plan de formation dans les entreprises, de la formalité à l’outil stratégique. Paris : Commissariat général à la stratégie et à la prospective, juin 2013, 150 p.
Rédaction
core  

Gender Affirming Surgery During Canadian Plastic Surgery Residency: A Survey of Plastic and Reconstructive Surgery Residents' Experiences. [PDF]

Plast Surg (Oakv)
Zeitouni C, Speak A, Leroux F, Bonapace-Potvin M, Tremblay D.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source