Results 231 to 240 of about 62,891,156 (300)

Patient-Specific Vascular Anatomy for Bedside Safety: A Targeted Narrative Review and the VASC-N Framework. [PDF]

Nurs Rep
Sanchis-Gimeno JA, Zuld AB, León-Rojas JE, Valenzuela-Fuenzalida JJ, Bruna-Mejías A, Oyanedel-Amaro G, Orellana-Donoso M.   +6 more
europepmc   +1 more source

Proposition de plan pour un module de formation : Transition juste et équité sociale.

Les cahiers de pédagogies radicales
openaire   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Labia Majora Symmetrization Using De-epithelialized Deep External Pudendal Artery Tubular Flap. [PDF]

Plast Reconstr Surg Glob Open
Pereira OJ, Ely JB, Lee KH.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Protein persulfidation: a ubiquitous modification regulating a broad spectrum of biological processes. [PDF]

J Exp Bot
Romero LC, Carrillo R, Montesinos-Pereira D, Luque C, Aroca A, Gotor C.   +5 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The evolutionary origins of streptophyte multicellularity. [PDF]

New Phytol
Darienko T, Kunz CF, Goldbecker ES, Endriulaitytė E, Bierenbroodspot MJ, Lorenz M, Irisarri I, Pröschold T, Bürstenbinder K, Buschmann H, de Vries J.   +10 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source