Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
La psychothérapie assistée par des agents psychédéliques: Un paradigme émergent. [PDF]
Shane D, Akhtar S, Hapke E.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Comparison of 'quilting sutures' with 'conventional sutures and drain placement' after mastectomy: protocol for the BE-Quilt - a multicentre, pragmatic randomised controlled trial. [PDF]
De Winter S +7 more
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Processus organisationnels et pratiques cliniques pour la gestion de la douleur chronique en soins primaires : une offre de service découlant du plan d'action en douleur chronique 2021-2026 ministériel du Québec, Canada. [PDF]
Lavoie-Dias G +25 more
europepmc +1 more source
En prenant comme point de départ la situation linguistique en Europe, cette contribution se propose de montrer comment sera organisée dans le cadre du projet Passepartout en Suisse alémanique la mise en place d’un enseignement du français langue ...
Christine Le Pape Racine
doaj
Ce mémoire est un des requis des études de Masters TFFL (Teaching French as a Foreign Language) à UCT (University of Cape Town) dont le but est de montrer l’acquisition des compétences par la mise en place d’une recherche-développement. Il porte sur la formation des enseignants de FLE (Français Langue Etrangère) dans notre pays, le Zimbabwe, et ...
openaire +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
The unorthodox aquaporin-12L ortholog is essential for oogenesis in the crustacean Artemia franciscana. [PDF]
Rey-Alfonso Á +3 more
europepmc +1 more source

