Results 191 to 200 of about 64,590,104 (297)

Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn's disease-associated Escherichia coli toward enhanced pathogenicity. [PDF]

J Crohns Colitis
Rytter H, Chevarin C, Martin L, Bruder E, Denizot J, Tenaillon O, Espéli O, Birer A, Barnich N, Viennois E, Chassaing B.   +10 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Oxidative and Mitochondrial Status of Vitrified Equine In Vitro Matured Oocytes Using Temperature-Specific Equilibration Protocols. [PDF]

Reprod Domest Anim
Gago S, Vendrell-Flotats M, Diaz-Muñoz J, Soriano-Moya M, Acacio M, Mestres E, Costa-Borges N, Mogas T.   +7 more
europepmc   +1 more source

Plan de estudios de la Carrera de Profesorado de Enseñanza Media y Superior en Bibliotecología y Ciencia de la Información. Adecuación 2024 del plan de estudios de 1999 - RESCS-2024-2048-E-UBA-REC/ RESCS-2025-1125-E-UBA-REC

Plan de estudios de la Carrera de Profesorado de Enseñanza Media y Superior en Bibliotecología y Ciencia de la Información.
Departamento de Bibliotecología y Ciencia de la Información
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Formation Plan de Gestion des Données (PGD)

, 2018
Auzoux, Sandrine, Corbiere, Pauline, Dedieu, Laurence, Paradis, Sébastien   +3 more
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Dosimetric impact of baseline shift plan in a magnetic resonance linear accelerator according to target motion and plan characteristics. [PDF]

J Appl Clin Med Phys
Tanaka S, Kadoya N, Takahashi Y, Koga S, Katsuta Y, Arai K, Hoshino T, Xiao Y, Lee W, Takahashi N, Umezawa R, Jingu K.   +11 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source