Results 121 to 130 of about 62,891,156 (300)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Plan de aforos. Red secundaria 2000: Granada
Andalucía. Consejería de Obras Públicas y Transportes; Andalucía. Dirección General de Carreteras; Andalucía. Servicio de Explotación y TecnologíaContiene: mapa red secundaria 2000 Granada, escala 1/400000- CD-Rom Plan de aforos 2000 ...
Andalucía. Consejería de Obras Públicas y Transportes +2 more
core
En France, les INSPÉ (Instituts nationaux supérieurs du professorat et de l’Éducation) forment les étudiants aux métiers du professorat, de l’éducation et de la formation.
Léa Degeuse, Alain Sénécail
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
What if the easiest thing you did today was start a college savings plan? Spanish
Logos: Oregon College Savings Plan; Oregon State TreasuryThis archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core
Les secteurs adultes de formation secondaire au Québec (formation générale aux adultes, FGA et formation professionnelle, FP) constituent des milieux scolaires qui contribuent fortement à la qualification minimale et professionnelle des jeunes âgés entre
Sarah-Emilie Labonté, Julie Marcotte
doaj +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Une gestion globale et solidaire des paysages de la Sèvre Nantaise
La Sèvre Nantaise est un affluent de la rive gauche de la Loire. Au carrefour de l'Anjou, de la Bretagne et du Poitou, les paysages qu'elle anime sont diversifiés tout en étant unis par une dominante bocagère au relief faiblement accentué.
M.A. RANNOU
doaj

