Results 161 to 170 of about 1,588,042 (310)

Nouveau plan de formation pour les assistantes mdicales CFC [PDF]

Bulletin des Médecins Suisses, 2019
openaire   +1 more source

Valorisation salariale de la formation professionnelle continue et production de compétences dans le système éducatif : le cas de la France et de l'Allemagne

, 1998
http://www.trainingvillage.gr/International audienceBecause it helps broaden the range of skills of people in industry, continuing training is regarded as contributing to individuals' career advancement by creating opportunities for better pay and ...
Béret, Pierre, Dupray, Arnaud
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Footprint morphology sheds light on running strategies in non-avian theropods. [PDF]

Sci Rep
Díaz-Martínez I, Navarro-Lorbés P, Isasmendi E, Páramo A, Gascó-Lluna F, Torices A, Ruiz J, Viera LI, Sáez-Benito P, Farlow J, Leonardi G, Pereda-Suberbiola X, Citton P.   +12 more
europepmc   +1 more source

Memoire : formation des enseignants de FLE dans les ecoles secondaires de Mutare au Zimbabwe : analyse des besoins et plan de formation

, 2011
Ce mémoire est un des requis des études de Masters TFFL (Teaching French as a Foreign Language) à UCT (University of Cape Town) dont le but est de montrer l’acquisition des compétences par la mise en place d’une recherche-développement. Il porte sur la formation des enseignants de FLE (Français Langue Etrangère) dans notre pays, le Zimbabwe, et ...
openaire   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Photolysis of CO₂ Carbamate for Hydrocarboxylation Reactions. [PDF]

J Am Chem Soc
Azzi E, Rodríguez-Martínez M, Kolusu SRN, Scarfiello J, Varela JA, Nappi M.   +5 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Redox reactions in subducted CaCO₃-Fe-SiO₂ as a potential source of superdeep diamond inclusions. [PDF]

Sci Rep
Guo M, Li X, Mao Z, Li F, Li L, Zhou Q.
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source