Results 191 to 200 of about 1,588,042 (310)

Conception d\u27un plan de formation des étudiants de premier cycle de la section sciences du Service commun de la documentation de l\u27Université Claude-Bernard Lyon 1 [PDF]

Barron, Géraldine, Bonnel, Sylvie, Charreaux, Stéphanie, Rollet, Nathalie   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Targeting the complement system in ANCA-associated vasculitis management. [PDF]

Rheumatology (Oxford)
de Groot K.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Inactivation of Cysteine Synthase CysK-A enhances flocculation, biofilm formation, and sensitivity to oxidative stress in <i>Azospirillum brasilense</i> Sp7. [PDF]

Biofilm
Herrera-Galindo J, Alcantara-Rosales CA, Ojeda OM, Xiqui-Vázquez ML, Mancilla-Simbro C, Reyes-Carmona S, Baca BE, Ramírez-Mata A.   +7 more
europepmc   +1 more source

Plan de formation [PDF]

Casseyre, Pierrette
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Oxidation of Amorphous Porous VO_x at Low Temperatures for the Formation of Thermochromic VO₂ Films. [PDF]

Nanomaterials (Basel)
Acosta-Rivera H, Rico V, Ferrer FJ, Rojas TC, Alvarez R, Martin N, González-Elipe AR, Palmero A.   +7 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Role of CEBPa in trophectoderm competence installment. [PDF]

Sci Adv
Wei X, Salvador-Martinez I, Meglicki M, Plana-Carmona M, Klonizakis A, Pernaute B, Irimia M, Stik G, Popovic M, Garcia GT, Heyn H, Zernicka-Goetz M, Graf T.   +12 more
europepmc   +1 more source