Results 61 to 70 of about 146,810 (268)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Revista Investigación y Formación Pedagógica, 2017 El objetivo fue desarrollar un Plan de Acción de formación docente en educar para la sostenibilidad a partir de la promoción de hábitos de vida saludable y sostenible desde la Escuela. Se seleccionó como método investigación - acción participativa.
Mery Faviola Escobar, Lucy T Useche
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Canadian Journal for New Scholars in Education, 2015 Les enseignants du secteur de la formation professionnelle au Québec se distinguent par leur recrutement et leur insertion dans la profession.
Andréanne Gagné
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Cahiers AgriculturesL’usage des pesticides, technologie peu onéreuse pour lutter contre les ennemis des cultures, est en pleine croissance dans l’agriculture africaine. Les pesticides sont pourtant source de nombreuses externalités négatives.
De La Paix Bayiha Gérard +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
La interdisciplinariedad y la formación profesional: una reflexión desde la disciplina de física
Góndola, Enseñanza y Aprendizaje de las Ciencias, 2015 El sistema educativo universitario cubano se ha enfrentado a varios retos en la actualidad, uno de ellos es la interdisciplinariedad. Esta metodología dentro del proceso docente se considera imprescindible en los primeros años de cualquier carrera ...
Yaima Rodríguez Peña
doaj +1 more source
Plans spécifiques de formation pour de nouveaux enseignants pour l’enseignement online
, 2022 [ES] Este capítulo, incluido en la obra "Formation des enseignants-chercheurs" se centra en las estrategias institucionales para la transformación digital y la mejora de la calidad docente, sirviendo como guía para la implementación de unidades de formación estables.
López Aguado, Mercedes +2 more
openaire +2 more sources