Results 201 to 210 of about 1,588,042 (310)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Unravelling the triad of penicillin-binding proteins, β-lactamase activity, and mRNA dynamics in Pseudomonas aeruginosa AmpC induction. [PDF]

J Antimicrob Chemother
Montaner M, Montes M, Alajarin F, López-Argüello S, Oliver A, Moya B.   +5 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Beyond Structure: The Role of the Outer Integument in Embryo, Endosperm, and Seed Development in Annona. [PDF]

Physiol Plant
Garcia-Lezama M, Hormaza JI, Lopez-Gomez E, Fernandez-Pozo N, Lora J.   +4 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Formation Plan de Gestion des Données (PGD)

, 2018
Auzoux, Sandrine, Corbiere, Pauline, Dedieu, Laurence, Paradis, Sébastien   +3 more
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Spectral and temporal differentiation between integral and contaminant chlorophyll <i>a</i> in the cytochrome <i>b</i>₆<i>f</i> complex.

Phys Chem Chem Phys
Chauvet AAP, Agarwal R, Cramer WA.
europepmc   +1 more source

Substrate-Selective Temperature-Controlled Synthesis of Thiophene Derivatives at Interfaces. [PDF]

Angew Chem Int Ed Engl
Pérez-Elvira E, Barragán A, Vicent DJ, Jóver Ó, Gallardo A, García-Frutos A, Černa L, Lauwaet K, Santos J, Perles J, Gallego JM, Miranda R, Urgel JI, Björk J, Di Giovannantonio M, Martín N, Écija D.   +16 more
europepmc   +1 more source

Approche des dynamiques spatio-temporelles de la formation de Saint-Emilion à travers le plan de 1845

, 2011
Antérieur aux grandes transformations urbanistiques subactuelles, le plan cadastral de 1845 constitue la source planimétrique la plus ancienne et la plus précise dont on dispose sur Saint-Emilion. L'analyse morphologique de cette source procède en deux temps.
openaire   +1 more source