Results 51 to 60 of about 175,184 (309)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
PARTICULARITĂȚILE PEDAGOGICE ALE FORMĂRII ORIENTĂRILOR VALORICE LA STUDENȚI PRIN ARTA COREGRAFICĂ
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2018 În articol este abordată problema privind formarea orientărilor valorice la studenți prin arta coregrafică din diferite perspective: general-pedagogică, teleologică și metodologică.
Maia DOHOTARU
doaj
Visite de la bibliothèque : découverte des espaces et des services
, 2019 Cette séance de formation est proposée à des étudiants de classe préparatoire lors de leur première visite de la Bnu de Strasbourg. Il s'agit de leur présenter l'établissement, les espaces, les collections et les principaux services, afin qu'il soient ...
Service Formation (8404272) +1 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Les déterminants de la formation dans les entreprises du Bâtiment
, 1987 This second part of the book - Formations et Emplois qualifiés. Les transformations dans le bâtiment en France et au Royaume-Uni - focuses the analysis of the dynamics of companies in order to understand their investment in training.
Appay, Beatrice
core +1 more source
Expérience d'un montage d'un plan de formation du français sur objectif universitaire (FOU) pour les étudiants des filières scientifiques dans le supérieur algérien [PDF]
, 2012 Notre décision de monter un plan de formation pour les étudiants des filières scientifiques en FOU émane d'un constat d'échec dans la construction de connaissances dans ces filières.
Mounia Aicha, Sebane
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Canadian Journal for New Scholars in Education, 2015 Les enseignants du secteur de la formation professionnelle au Québec se distinguent par leur recrutement et leur insertion dans la profession.
Andréanne Gagné
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source