Results 121 to 130 of about 62,890,502 (300)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Plan de aforos. Red secundaria 2000: Granada

open access: yes, 2001
Andalucía. Consejería de Obras Públicas y Transportes; Andalucía. Dirección General de Carreteras; Andalucía. Servicio de Explotación y TecnologíaContiene: mapa red secundaria 2000 Granada, escala 1/400000- CD-Rom Plan de aforos 2000 ...
Andalucía. Consejería de Obras Públicas y Transportes   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Le projet professionnel des jeunes hommes inscrits en formation générale ou dans une formation professionnelle du secteur de la construction : le rôle médiateur de l’estime de soi, du sentiment de contrôle et de la détresse psychologique

open access: yesCanadian Journal of Education, 2014
Les secteurs adultes de formation secondaire au Québec (formation générale aux adultes, FGA et formation professionnelle, FP) constituent des milieux scolaires qui contribuent fortement à la qualification minimale et professionnelle des jeunes âgés entre
Sarah-Emilie Labonté, Julie Marcotte
doaj   +2 more sources

Relación entre la nueva formación en enfermería y el postgrado de la carrera Relation between the new formation in nursing, and the postgrade of the carrier

open access: yesRevista Habanera de Ciencias Médicas, 2010
El surgimiento de las Escuelas Emergentes de Enfermería en Cuba, significó para la Carrera una formación de nuevo tipo. La masividad e integración del sistema de la Enseñanza Media de la profesión a la Enseñanza Superior, estuvieron entre los rasgos ...
Arturo Alexander Segura Massó   +1 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

What if the easiest thing you did today was start a college savings plan? Spanish

open access: yes, 2020
Logos: Oregon College Savings Plan; Oregon State TreasuryThis archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Une gestion globale et solidaire des paysages de la Sèvre Nantaise

open access: yesSciences, Eaux & Territoires, 1997
La Sèvre Nantaise est un affluent de la rive gauche de la Loire. Au carrefour de l'Anjou, de la Bretagne et du Poitou, les paysages qu'elle anime sont diversifiés tout en étant unis par une dominante bocagère au relief faiblement accentué.
M.A. RANNOU
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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