Results 51 to 60 of about 149,597 (269)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Canadian Journal for New Scholars in Education, 2015 Les enseignants du secteur de la formation professionnelle au Québec se distinguent par leur recrutement et leur insertion dans la profession.
Andréanne Gagné
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Revista Investigación y Formación Pedagógica, 2017 El objetivo fue desarrollar un Plan de Acción de formación docente en educar para la sostenibilidad a partir de la promoción de hábitos de vida saludable y sostenible desde la Escuela. Se seleccionó como método investigación - acción participativa.
Mery Faviola Escobar, Lucy T Useche
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Plans spécifiques de formation pour de nouveaux enseignants pour l’enseignement online
, 2022 [ES] Este capítulo, incluido en la obra "Formation des enseignants-chercheurs" se centra en las estrategias institucionales para la transformación digital y la mejora de la calidad docente, sirviendo como guía para la implementación de unidades de formación estables.
López Aguado, Mercedes +2 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cahiers AgriculturesL’usage des pesticides, technologie peu onéreuse pour lutter contre les ennemis des cultures, est en pleine croissance dans l’agriculture africaine. Les pesticides sont pourtant source de nombreuses externalités négatives.
De La Paix Bayiha Gérard +3 more
doaj +1 more source
L’éducation au vivre ensemble en Suisse : analyse des plans d’études et enjeux de formation [PDF]
Éthique en éducation et en formation, 2020 Cet article propose un inventaire des usages de l’expression « vivre(-)ensemble » et de son correspondant allemandZusammenleben à partir des versions modèles des deux principaux plans d’études en Suisse. Il dresse une cartographie du vivre ensemble en identifiant les parties des plans d’études dans lesquelles cette notion est mobilisée et les ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source