Results 101 to 110 of about 146,810 (268)
Formation : "Les Plans de Gestion des Logiciels de la Recherche". Questions et Réponses sur le Modèle PRESOFT et les Plans de Gestion [PDF]
L’objectif de ce document est de reprendre certaines questions qui ont été posées par les participants à la formation « Les Plans de Gestion des Logiciels de la Recherche » qui a eu lieu les 23-24 mai 2024, à l’Université Gustave Eiffel (UGE), Paris-Est, voir http://igm.univ-mlv.fr/~teresa/presoft/2024FormationPlansGestionLogicielsRecherche/.
openaire +3 more sources
En France, les INSPÉ (Instituts nationaux supérieurs du professorat et de l’Éducation) forment les étudiants aux métiers du professorat, de l’éducation et de la formation.
Léa Degeuse, Alain Sénécail
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Bien communiquer sur sa thèse, suite.
Après une brève présentation sur lui-même, Edouard Paulino du Craft (Centre de recherche et d’appui pour la formation et ses technologies, qui travaille à l’ Epfl ) lance le débat : que signifie communiquer sur sa thèse ?
Philippe Heller
doaj
This paper describes two experiments designed to ascertain whether the way in which architectural plans are displayed on a computer screen influences the quality of their correction by humans, and identify the visual exploration strategies adopted in this type of task.
Fleury, Sylvain, Jamet, Eric
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Une gestion globale et solidaire des paysages de la Sèvre Nantaise
La Sèvre Nantaise est un affluent de la rive gauche de la Loire. Au carrefour de l'Anjou, de la Bretagne et du Poitou, les paysages qu'elle anime sont diversifiés tout en étant unis par une dominante bocagère au relief faiblement accentué.
M.A. RANNOU
doaj

