Results 21 to 30 of about 48,828 (263)

Evaluating the Advertising Effectiveness of Reading Promotion Projects of Iran Public Libraries Foundation in Attracting Users from the Library Members\' Viewpoints: A Case Study of Public Libraries of Zanjan Province [PDF]

تحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2018
Purpose: The present research aims to investigate the advertising effectiveness of Iran Public Libraries Foundation's reading projects in attracting users to the public libraries of Zanjan province from the viewpoint of their members.
mahnaz karimzadeh,
doaj  

Social madia in academic libraries: a swot analysis

Знак: проблемное поле медиаобразования, 2021
Social media offers libraries new ways to communicate, identify, and satisfy the information needs of library users. Although social media has several benefits, some challenges might be associated with its use.
Duong Thi Phuong Chi
doaj   +1 more source

Improvement of Public Library Services Quality: A Strategic Plan by Interpretive Structural Modeling and MICMAC (Case Study: Yazd City Public Libraries in Iran) [PDF]

تحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2017
Purpose: The purpose of this study was to develop a strategic plan to improve the quality of public libraries in order to resolve financial barriers and better internal processes using structural modeling of interpretations of the library experts ...
Seyed Habibollah Mirghafouri, zoherh karimi gogheri, Akram Shabani   +2 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Bibliotecas y marketing en red

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2009
Objetivos. Realizar una aproximación teórica sobre el concepto de marketing y su aplicación en bibliotecas a la luz de las transformaciones tecnológicas y sociales protagonizadas por los medios sociales y las aplicaciones de la web social y elaborar unas
González Fernández-Villavicencio, Nieves
doaj   +1 more source

A free toolkit to foster open access agreements

Insights: The UKSG Journal, 2023
In November 2021, with the support of the Association of Learned and Professional Society Publishers (ALPSP) and cOAlition S, four ‘task and finish’ working groups were established. The authors facilitated and supported these groups.
Alicia Wise, Lorraine Estelle
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source