Results 141 to 150 of about 6,209,750 (299)

Decommissioning plan for the WPI nuclear reactor

open access: yes, 1999
During the coming decade, the licenses of an entire generation of nuclear reactors will expire, including the WPI reactor. According to 10CFR50, the government regulations for licensing reactors and other nuclear facilities, in order to renew a license ...
Bernard, David Robert   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

ITPR3 promotes liver fibrosis by damaging hepatocytes via the Ca2+/NF-B/LECT2 pathway. [PDF]

open access: yesSci Rep
Zhao X   +7 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Research progress and trends on PET/CT imaging of pancreatic cancer: a bibliometric analysis. [PDF]

open access: yesDiscov Oncol
Wang X   +7 more
europepmc   +1 more source

RCNET Module: Nuclear Mavericks

open access: yes
Module Description:This Nuclear Mavericks module consists of the Nuclear Mavericks Info Sheet, RCNET Module Nuclear Mavericks PDF, Lesson Plan, a PowerPoint Presentation, and Discussion and Presentation Rubrics intended to use with the textbook Nuclear ...

core  

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