Results 151 to 160 of about 6,209,750 (299)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Lactate-Induced Liquid-Liquid Phase Separation of HIF-1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer. [PDF]

Cell Prolif
Fu C, Chen X, Huang H, Zhang L, Huang H, Jiang F, Lei F, Yu H, Liu J, Zhang H, Dai K, Wu Z, Li H, Dai XJ, Mao S.   +14 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Out-of-beam artifact suppression in charged nuclear fragment based carbon-ion radiotherapy monitoring. [PDF]

Med Phys
Kirchgässner R, Martišíková M, Schlegel P, Ochoa-Parra P, Harrabi S, Jäkel O, Debus J, Kelleter L.   +7 more
europepmc   +1 more source

White paper on nuclear astrophysics and low energy nuclear physics Part 1: Nuclear astrophysics

, 2017
A. Arcones, D. Bardayan, T. Beers, L. Bernstein, J. Blackmon, B. Messer, B. Brown, Edward F. Brown, C. Brune, A. Champagne, A. Chieffi, A. Couture, P. Danielewicz, R. Diehl, M. Eleid, J. Escher, Brian D. Fields, Carla Fröhlich, F. Herwig, W. Hix, C. Iliadis, W. Lynch, G. McLaughlin, B. Meyer, A. Mezzacappa, F. Nunes, Brian W. O'Shea, M. Prakash, B. Pritychenko, S. Reddy, E. Rehm, G. Rogachev, Robert E. Rutledge, H. Schatz, M. S. Smith, I. Stairs, Andrew W. Steiner, T. Strohmayer, F. Timmes, D. Townsley, M. Wiescher, R. Zegers, M. Zingale   +42 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A Phantom Investigation of the Robustness and Adaptability of a Novel PET LINAC During Lung Cancer Biology-Guided Radiotherapy (BgRT) Characterized by Unplanned Perturbations in the Tumor Trajectory. [PDF]

Cancers (Basel)
Teboh R, Osunkwor O, Lewis B.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Flexibility on a Firm Foundation-The Central Electricity Generating Board's Promotion of Nuclear Power in Oldbury-on-Severn. [PDF]

NTM
Götter C.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source