Results 151 to 160 of about 785,168 (303)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Enhancement of dose distribution using tissue compensators in boron neutron capture therapy. [PDF]

J Appl Clin Med Phys
Sasaki A, Hu N, Nojiri M, Akita K, Yoshikawa S, Kohigashi Y, Nihei K, Aihara T, Takeno S, Yoshino Y, Tanaka H, Ono K.   +11 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Initial Institutional Experience and Workflow of Biology-Guided Radiotherapy (BgRT) for a Patient With Non-small Cell Lung Cancer. [PDF]

Cureus
Kwon YS, Cai B, Shen C, Banks TI, Prasad R, Oz OK, Dan T, Garant A, Westover K, Sher D, Timmerman R, Badiyan S.   +11 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC). [PDF]

Hum Genomics
Xu Y, Cao Y, Yang J, Yu X, Yang L, Xie Y, Zhao J, Zhang Y.   +7 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Patient-specific quality assurance for extremely small field sizes using 3D in vivo dosimetry in fractionated stereotactic radiosurgery for brain metastases. [PDF]

J Appl Clin Med Phys
Jumonji K, Takatsu J, Hara N, Fan R, Shimomura R, Inoue T, Iijima K, Okonogi N, Murakami N, Shikama N.   +9 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Results from a prospective registry of ¹⁸F-Fluciclovine PET/CT use in prostate cancer management: a cautionary lesson for implementation of PSMA PET. [PDF]

Am J Nucl Med Mol Imaging
Blinka S, Wong RL, Holt SK, Lo E, Cheng HH, Conrad N, Loesch H, Toulouse AE, Lai M, Hsieh AC, Grivas P, Yezefski T, Wright JL, Schweizer MT, Montgomery RB, Chen DL, Zeng J, Lin DW, Yu EY.   +18 more
europepmc   +1 more source