Results 61 to 70 of about 785,168 (303)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Equation of State of nuclear matter in a Virial expansion of nucleons and nuclei

, 2010
We study the equation of state (EOS) of nuclear matter at subnuclear density in a Virial expansion for a nonideal gas. The gas consists of neutrons, protons, alpha particles, and 8980 species of nuclei with $A \ge 12$ and masses from the finite-range ...
Horowitz, C. J., Shen, G., Teige, S.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The core flux of the brightest 10 micron galaxies in the southern sky [PDF]

, 2008
Aims. Near diffraction-limited images have been taken at 8.9, 11.9, and 12.9 micron for the brightest extragalactic sources in the southern sky, in order to optimally plan N-band observations with MIDI (MID-infrared Interferometric instrument) at the ...
Heijligers, B., Henning, T., Jaffe, W., Kaufl, H. U., Meisenheimer, K., Raban, D., Rottgering, H.   +6 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Deuteron nuclear data for the design of accelerator-based neutron sources: Measurement, model analysis, evaluation, and application

EPJ Web of Conferences, 2017
A comprehensive research program on deuteron nuclear data motivated by development of accelerator-based neutron sources is being executed. It is composed of measurements of neutron and gamma-ray yields and production cross sections, modelling of deuteron-
Watanabe Yukinobu, Kin Tadahiro, Araki Shouhei, Nakayama Shinsuke, Iwamoto Osamu   +4 more
doaj   +1 more source

Overview of Security Plan for Offshore Floating Nuclear Plant [PDF]

, 2018
A new Offshore Floating Nuclear Plant (OFNP) concept with high potential for attractive economics and an unprecedented level of safety is presented, along with an overview of work done in the area of security.
Birch, Arthur, Buongiorno, Jacopo, Isdanavich, Thomas, Kindfuller, Vincent J., Stevens, Harvey, Thomas, Ron, Todreas, Neil E   +6 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Energy Crisis and the Need to Enhance Nuclear Energy in Pakistan

NUST Journal of Engineering Sciences, 2010
Energy crisis is the immense shortfall in the supply of energy resources including electricity. Due to increase in the consumption of electricity, Pakistan is facing the worst power crisis of its history.
Faisal Asfand, Muhammad Sadiq
doaj   +1 more source