Results 51 to 60 of about 254,621 (262)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Extension of Paul Erdős graph on hypergroups

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
This paper introduces ultra non-commutative graphs derived from ultra non-commutative hypergroups. Vertices represent ultra non -commutative elements of the hypergroup U, defined as AU = {x ∈ U |Ǝy ∈ U, y ○ x ∩ x ○ y = ∅}. An edge connects vertices x and
Shamsadini S., Aghabozorgi H., Jafarpour M., Hoskova-Mayerova S.   +3 more
doaj   +1 more source

Contactless object manipulation using multiple air jets on planar surface (Experimental case studies of control method for the multiple objects using four air jets nozzles)

Nihon Kikai Gakkai ronbunshu, 2016
We present a method for contactless manipulation of multiple small objects in a plane using multiple air jets. When the objects are initially clustered as a group, the group's center of gravity is used as a representative point and the entire group ...
Tsubasa MATSUSHITA, Naoki TSUCHIHASHI, Satoshi IWAKI, Takeshi TAKAKI, Toshiharu KOSAKU   +4 more
doaj   +1 more source

An Ultra-Wide Band Radome for High-Performance and Dual-Polarized Radar and Communication Systems

IEEE Access, 2020
This paper presents a new design technique to develop a multi-layer radome for ultra-wide-band, dual-polarized radar and communication systems. In the proposed technique, a multi-layer radome is designed using a combination of A-sandwich structures ...
Zeeshan Qamar, Jorge L. Salazar-Cerreno, Nafati Aboserwal   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Technological Indicators of the Operation of Cutting Blanks from Sheet Material with a Wire Tool with a Modified Surface by Electroerosion Method

Механика машин, механизмов и материалов, 2020
The article is devoted to the experimental evaluation of the effect of EDM modifying the original smooth surface of the wire tool on its technological parameters when cutting different sheet materials, in particular, on cutting ability, surface quality ...
Mikhail G. Kiselev, Andrei V. Moskalenko, Pavel S. Bogdan, Sergey G. Monich, Alexandr A. Anschitc   +4 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

An Investigation of Body Diode Reliability in Commercial 1.2 kV SiC Power MOSFETs with Planar and Trench Structures

Micromachines
The body diode degradation in SiC power MOSFETs has been demonstrated to be caused by basal plane dislocation (BPD)-induced stacking faults (SFs) in the drift region.
Jiashu Qian, Limeng Shi, Michael Jin, Monikuntala Bhattacharya, Atsushi Shimbori, Hengyu Yu, Shiva Houshmand, Marvin H. White, Anant K. Agarwal   +8 more
doaj   +1 more source

Nilpotent graphs with crosscap at most two

AKCE International Journal of Graphs and Combinatorics, 2018
Let be a commutative ring with identity. The nilpotent graph of , denoted by , is a graph with vertex set , and two vertices and are adjacent if and only if is nilpotent, where .
A. Mallika, R. Kala
doaj   +1 more source