Results 41 to 50 of about 3,865 (189)

Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

open access: yeseLife, 2014
Planarian flatworms regenerate every organ after amputation. Adult pluripotent stem cells drive this ability, but how injury activates and directs stem cells into the appropriate lineages is unclear.
Carolyn E Adler   +3 more
doaj   +1 more source

Hedgehog signaling regulates gene expression in planarian glia

open access: yeseLife, 2016
Hedgehog signaling is critical for vertebrate central nervous system (CNS) development, but its role in CNS biology in other organisms is poorly characterized. In the planarian Schmidtea mediterranea, hedgehog (hh) is expressed in medial cephalic ganglia
Irving E Wang   +4 more
doaj   +1 more source

A Systematic Review on Non-mammalian Models in Epilepsy Research

open access: yesFrontiers in Pharmacology, 2018
Epilepsy is a common neurological disorder characterized by seizures which result in distinctive neurobiological and behavioral impairments. Not much is known about the causes of epilepsy, making it difficult to devise an effective cure for epilepsy ...
Muhammad Faiz Johan Arief   +6 more
doaj   +1 more source

EMPLEO DE LA REGENERACIÓN DE LA PLANARIA DE AGUA DULCE GIRARDIA FESTAE (BORELLI, 1898) (TRICLADIDA: DUGESIIDAE) PARA EVALUAR LA TOXICIDAD DEL CARBOFURANO*

open access: yesNeotropical helminthology, 2021
El uso de plaguicidas en el mundo aumenta en forma desproporcionada cada día, por lo que se necesitan urgentemente adecuados agentes bioindicadores. Para una oportuna evaluación del riesgo ambiental de los ambientes acuáticos dulceacuícolas en Perú, se ...
J. Iannacone, Miguel Tejada
semanticscholar   +1 more source

Why we age

open access: yesBiological Reviews, EarlyView.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians

open access: yeseLife, 2016
In contrast to transcriptional regulation, the function of alternative splicing (AS) in stem cells is poorly understood. In mammals, MBNL proteins negatively regulate an exon program specific of embryonic stem cells; however, little is known about the in
Jordi Solana   +11 more
doaj   +1 more source

The spread of non‐native species

open access: yesBiological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock   +16 more
wiley   +1 more source

Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38

open access: yeseLife, 2016
The interrelationship between endogenous microbiota, the immune system, and tissue regeneration is an area of intense research due to its potential therapeutic applications.
Christopher P Arnold   +8 more
doaj   +1 more source

A powerful and versatile new fixation protocol for immunohistology and in situ hybridization that preserves delicate tissues in planaria

open access: yesbioRxiv, 2021
Whole-mount in situ hybridization (WISH) is a powerful and widely used technique to visualize the expression pattern of genes in different biological systems.
Carlos Guerrero-Hernández   +3 more
semanticscholar   +1 more source

Ecotoxicological Evaluation of the Antimicrobial Butylparaben in Edaphic Organisms Using Multiple Biomarkers

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Butylparaben (BuP) recurrently contaminates soils worldwide, mainly by incorporating sewage sludge into cultivated areas, using wastewater in irrigation, and leaching contaminated soils. However, there are few studies on the ecotoxicological effects of this paraben on edaphic organisms.
Lorena Maihury Santos Tsubouchi   +13 more
wiley   +1 more source

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