Results 41 to 50 of about 1,265 (189)

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

In‐Memory Continuous‐Time SAT Solver Based on Bidirectional 11‐T SRAM Macro

Advanced Intelligent Systems, EarlyView.
This article reported a continuous‐time (CT) Boolean satisfiability (SAT) problem solver using bidirectional 11T‐SRAM macro. The proposed system operates asynchronously using capacitor‐based gradient integration and maximizes the parallelism for SAT solving by in‐memory computing (IMC).
Dongseok Kwon, Tinish Bhattacharya, George Higgins Hutchinson, Dmitri Strukov   +3 more
wiley   +1 more source

A new invariant of plane bipartite cubic graphs

Discrete Mathematics, 1992
This paper presents a new polynomial invariant of plane bipartite cubic graphs. This invariant is the restriction to plane graphs of a certain invariant of oriented bipartite cubic graphs embedded in 3-space, which corresponds in the case of links to a one-variable specialization of the `homfly' polynomial.
openaire   +2 more sources

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Eco‐Innovation, Economic Complexity, and Sustainability: A Bibliometric and Systematic Literature Review

Business Strategy and the Environment, EarlyView.
ABSTRACT This study systematizes the literature on eco‐innovation and economic complexity, aiming to understand how the sophistication of productive structures shapes countries' capacity to develop environmentally responsible innovations, and how eco‐innovation may, in turn, influence productive sophistication.
Gregory Matheus Pereira de Moraes, Diogo Ferraz   +1 more
wiley   +1 more source

Graphs Drawn With Some Vertices per Face: Density and Relationships

IEEE Access
Graph drawing beyond planarity is a research area that has received an increasing attention in the last twenty years, driven by the necessity to mitigate the visual complexity inherent in geometric representations of non-planar graphs. This research area
Carla Binucci, Giuseppe Di Battista, Walter Didimo, Vida Dujmovic, Seok-Hee Hong, Michael Kaufmann, Giuseppe Liotta, Pat Morin, Alessandra Tappini   +8 more
doaj   +1 more source

Conditional Randomization Tests for the Specification of Interference Structure

Journal of Applied Econometrics, EarlyView.
ABSTRACT This study proposes specification tests for interference structure in causal inference with spillovers. We focus on experimental settings in which the treatment assignment mechanism is known. To test whether a given exposure mapping adequately summarizes the true interference structure, we develop conditional randomization tests by utilizing ...
Tadao Hoshino, Takahide Yanagi
wiley   +1 more source

Signed Projective Cubes, a Homomorphism Point of View

Journal of Graph Theory, EarlyView.
ABSTRACT The (signed) projective cubes, as a special class of graphs closely related to the hypercubes, are on the crossroad of geometry, algebra, discrete mathematics and linear algebra. Defined as Cayley graphs on binary groups, they represent basic linear dependencies.
Meirun Chen, Reza Naserasr, Alessandra Sarti   +2 more
wiley   +1 more source