Results 41 to 50 of about 82,884 (244)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Free Edge Lengths in Plane Graphs [PDF]
Proceedings of the thirtieth annual symposium on Computational geometry, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Connelly, Robert +7 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Decomposing plane cubic graphs
European Journal of Combinatorics, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kenta Ozeki, Dong Ye
openaire +2 more sources
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
THE ENTIRE FACE IRREGULARITY STRENGTH OF A BOOK WITH POLYGONAL PAGES
Barekeng, 2015 A face irregular entire labeling is introduced by Baca et al. recently, as a modification of the well-known vertex irregular and edge irregular total labeling of graphs and the idea of the entire colouring of plane graph.
Meilin I. Tilukay, Venn Y. I. Ilwaru
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
On the Laplacian spectral radii of Halin graphs
Journal of Inequalities and Applications, 2017 Let T be a tree with at least four vertices, none of which has degree 2, embedded in the plane. A Halin graph is a plane graph constructed by connecting the leaves of T into a cycle. Thus the cycle C forms the outer face of the Halin graph, with the tree
Huicai Jia, Jie Xue
doaj +1 more source