Results 61 to 70 of about 1,410,460 (300)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Every Graph Is an Integral Distance Graph in the Plane
Journal of Combinatorial Theory, Series A, 1997 For a finite subset of the plane the pairs of points for which their euclidean distance is an integer defines the corresponding integral distance graph. It is shown that every finite simple graph may be represented in such a way.
Hiroshi Maehara +2 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
ω -Searchlight Obedient Graph Drawings [PDF]
, 2001 A drawing of a graph in the plane is ω-searchlight obedient if every vertex of the graph is located on the centerline of some strip of width ω, which does not contain any other vertex of the graph.
Barequet, Gill, Gill Barequet
core +1 more source
Evaluating the Tutte Polynomial for Graphs of Bounded Tree-Width [PDF]
, 1998 It is known that evaluating the Tutte polynomial, $T(G; x, y)$, of a graph, $G$, is $\#$P-hard at all but eight specific points and one specific curve of the $(x, y)$-plane.
Noble, S D
core +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A Linear Algorithm for Optimal Orthogonal Drawings of Triconnected Cubic Plane Graphs
, 1998 An orthogonal drawing of a plane graph G is a drawing of G in which each edge is drawn as a sequence of alternate horizontal and vertical line segments.
Nakano, Shin-Ichi +2 more
core +1 more source
Drawing planar graphs with prescribed face areas
Journal of Computational Geometry, 2018 We study drawings of planar graphs where every inner face has a prescribed area. A plane graph is 'area-universal' if for every area assignment on the inner faces, there exists a straight-line drawing realizing the assigned areas.
Linda Kleist
doaj +1 more source