Results 71 to 80 of about 569,825 (280)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
On Face Irregular Evaluations of Plane Graphs
Discussiones Mathematicae Graph Theory, 2022 We investigate face irregular labelings of plane graphs and we introduce new graph characteristics, namely face irregularity strength of type (α,β,γ). We obtain some estimation on these parameters and determine the precise values for certain families of ...
Bača Martin +3 more
doaj +1 more source
Isoperimetric Constants of Infinite Plane Graphs [PDF]
Discrete & Computational Geometry, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lawrencenko, Serge +2 more
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 2009 We consider a generalization of the Gabriel graph, the witness Gabriel graph. Given a set of vertices P and a set of witnesses W in the plane, there is an edge ab between two points of P in the witness Gabriel graph GG-(P,W) if and only if the closed ...
Aronov, Boris +2 more
core +2 more sources
Separability and the genus of a partial dual
, 2012 Partial duality generalizes the fundamental concept of the geometric dual of an embedded graph. A partial dual is obtained by forming the geometric dual with respect to only a subset of edges.
Chmutov +11 more
core +2 more sources
3-Facial Coloring of Plane Graphs [PDF]
SIAM Journal on Discrete Mathematics, 2008 A plane graph is l-facially k-colourable if its vertices can be coloured with k colours such that any two distinct vertices on a facial segment of length at most l are coloured differently. We prove that every plane graph is 3-facially 11-colourable.
Havet, Frédéric +2 more
openaire +3 more sources
Implementing path coloring algorithms on planar graphs [PDF]
, 2017 Master's Project (M.S.) University of Alaska Fairbanks, 2017A path coloring of a graph partitions its vertex set into color classes such that each class induces a disjoint union of paths.
Bross, Daniel Aven
core