Results 71 to 80 of about 568,500 (305)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

L-Visibility Drawings of IC-planar Graphs

open access: yes, 2015
An IC-plane graph is a topological graph where every edge is crossed at most once and no two crossed edges share a vertex. We show that every IC-plane graph has a visibility drawing where every vertex is an L-shape, and every edge is either a horizontal ...
AM Dean   +6 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Infinitesimal rigidity in normed planes

open access: yes, 2018
We prove that a graph has an infinitesimally rigid placement in a non-Euclidean normed plane if and only if it contains a $(2,2)$-tight spanning subgraph.
Dewar, Sean
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

THE ENTIRE FACE IRREGULARITY STRENGTH OF A BOOK WITH POLYGONAL PAGES

open access: yesBarekeng, 2015
A face irregular entire labeling is introduced by Baca et al. recently, as a modification of the well-known vertex irregular and edge irregular total labeling of graphs and the idea of the entire colouring of plane graph.
Meilin I. Tilukay, Venn Y. I. Ilwaru
doaj   +1 more source

Witness Gabriel Graphs [PDF]

open access: yes, 2009
We consider a generalization of the Gabriel graph, the witness Gabriel graph. Given a set of vertices P and a set of witnesses W in the plane, there is an edge ab between two points of P in the witness Gabriel graph GG-(P,W) if and only if the closed ...
Aronov, Boris   +2 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

On the Laplacian spectral radii of Halin graphs

open access: yesJournal of Inequalities and Applications, 2017
Let T be a tree with at least four vertices, none of which has degree 2, embedded in the plane. A Halin graph is a plane graph constructed by connecting the leaves of T into a cycle. Thus the cycle C forms the outer face of the Halin graph, with the tree
Huicai Jia, Jie Xue
doaj   +1 more source

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