Results 81 to 90 of about 2,427,282 (299)

A plane graph representation of triconnected graphs

open access: yesTheoretical Computer Science, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ota, Shunsuke   +2 more
openaire   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

A Note On Vertex Colorings Of Plane Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2014
Given an integer valued weighting of all elements of a 2-connected plane graph G with vertex set V , let c(v) denote the sum of the weight of v ∈ V and of the weights of all edges and all faces incident with v.
Fabricia Igor   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Odd facial total-coloring of unicyclic plane graphs [PDF]

open access: yesDiscrete Mathematics Letters, 2022
Július Czap
doaj   +1 more source

Graphs embedded into finite projective planes

open access: yesContributions to Discrete Mathematics, 2015
We study embeddings of graphs in finite projective planes, and present related results for some families of graphs including complete graphs and complete bipartite graphs. We also make connections between embeddings of graphs and the existence of certain substructures in a plane, such as Baer subplanes and arcs.
Mellinger, Keith   +2 more
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

From Tutte to Floater and Gotsman: On the Resolution of Planar Straight-line Drawings and Morphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science
The algorithm of Tutte for constructing convex planar straight-line drawings and the algorithm of Floater and Gotsman for constructing planar straight-line morphs are among the most popular graph drawing algorithms.
Giuseppe Di Battista, Fabrizio Frati
doaj   +1 more source

The total face irregularity strength of some plane graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
A face irregular total -labeling of a 2-connected plane graph is a labeling of vertices and edges such that their face-weights are pairwise distinct. The weight of a face under a labeling is the sum of the labels of all vertices and edges surrounding ...
Meilin I. Tilukay   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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