Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Deformation of Poly-l-lactid acid (PLLA) under Uniaxial Tension and Plane-Strain Compression. [PDF]
Vozniak A, Bartczak Z.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Strain-induced magnetocrystalline anisotropy in L21 Co2FeSi: first-principles study
The Co2FeSi/Fe/Pb(Mg1/3Nb2/3)O3-PbTiO3 interface exhibits the strong magnetoelectric coupling arising from the magnetocrystalline anisotropy (MCA) of Co2FeSi. To enable the design of the MCA based on crystal structures and plane orientations, we examined
Ryota Watarai, Yoshihiro Gohda
doaj +1 more source
Numerical Evaluation of the Fracture Process of 41Cr4 Steel: Analysis of Cracks Grown in a Plane Strain State Domination Based on Experimental Results. [PDF]
Graba M.
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Manipulating absorption and diffusion of H atom on graphene by mechanical strain
Effects of the tensile strain on absorption and diffusion of hydrogen atoms on graphene have been studied by first-principles calculations. Our calculations suggested that there exists a barrier of 0.22 eV for H atom to diffuse from free space to ...
Ming Yang +5 more
doaj +1 more source
Finite Plane Strain Bending under Tension of Isotropic and Kinematic Hardening Sheets. [PDF]
Strashnov S, Alexandrov S, Lang L.
europepmc +1 more source
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Mechanical Performance and Void Structure Change of Foamed Cement Paste Subjected to Static and Cyclic Loading under Plane Strain Conditions. [PDF]
Zhang Z, Rao F, Ye G, Liu J.
europepmc +1 more source

