Results 181 to 190 of about 1,955 (227)

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

open access: yesAdvanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu   +18 more
wiley   +1 more source

The Origins & Reservoirs of Exocomets. [PDF]

open access: yesSpace Sci Rev
Bannister M   +13 more
europepmc   +1 more source

Hybrid Metal–Organic Framework‐Derived Dual Active Site Catalysts Enabling Surface‐Enriched Cathode and Modified Zinc Anode for Long‐Life Zinc–Air Batteries

open access: yesAdvanced Science, EarlyView.
This work demonstrates the implementation of MOF‐assisted anode and cathode materials for prolonged cycling of zinc‐air batteries with strong redox capability and structural stability. ABSTRACT The surface modification of zinc anodes and the development of effective cathode dual‐functional oxygen electrocatalysts remain of paramount interest for ...
Ramasamy Santhosh Kumar   +7 more
wiley   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

open access: yesAdvanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin   +7 more
wiley   +1 more source

Sustainable diets and functional foods for the prevention of cardio-metabolic diseases and sustainable development goals of the UNO. An international consensus of scientific statement of the international college of nutrition and 28th world congress on clinical nutrition, Bogor, Indonesia. [PDF]

open access: yesBMC Cardiovasc Disord
Ridwan H   +69 more
europepmc   +1 more source

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