Results 91 to 100 of about 3,967,482 (300)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Planning for Antifragility and Antifragility for Planning

open access: yes, 2018
We argue that antifragility is a valuable and contentful goal for planning, distinct from resilience. We present a possible conceptualisation and delineate the essential properties of an antifragile planning, its affinities with the capability approach, and discuss the possible sources of its legitimacy within the conception of a liberal-democratic ...
Blečić, Ivan, Cecchini, Arnaldo
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Training Model Designed to Strengthen and Improve the Pass for Juniors 10 – 12 Years

open access: yesBulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics
The purpose of this study is represented by the theoretical and methodical elaboration of a material intended for continuous use by coaches and teachers working with groups of juniors aged between 10 and 12 years.
S. Teris, I.I. Lakotos, V. Koronas
doaj   +1 more source

Organization for state comprehensive development planning and programming for the state of Kansas [1967]

open access: yes, 1967
"'701' project no. Kans P-43."SUMMARY OF FINDINGS -- INTRODUCTION -- STATE COMPREHENSIVE DEVELOPMENT PLANNING AND PROGRAMMING -- EXISTING PLANNING AND PROGRAMMING ACTIVITIES -- DEVELOPMENT POLICY: FORMULATION, EXECUTION AND APPRAISAL: COMMUNICATION ...
Oblinger & Smith
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Regions of Kansas : organizing for planning and development

open access: yes, 1966
"'701' project no. Kans. P-43."Regional Development In Kansas -- Coping With An Era Of Change -- State-Wide Programming And Planning -- Why Regional Planning And Development?
Kansas State University Center for Community Planning Services
core  

Wastewater Treatment Facilities: Inventory and Planning Guide

open access: yes, 1988
This report provides an overview of facilities, wastewater treatment planning, and agencies. It is designed to complement the "Monmouth County Sanitary Sewerage Facilities Map," published in June 1988.

core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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