Results 111 to 120 of about 3,967,482 (300)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Echoes of a decade in the plaNext – Next Generation Planning journal and the road ahead

PlaNext
plaNext – Next Generation Planning journal is an international, peer-reviewed, open-access e-journal founded by the AESOP Young Academics network.
Esra Kut Görgün, Nath Subhashree
doaj   +1 more source

Conversational Planning for Personal Plans

CoRR
The language generation and reasoning capabilities of large language models (LLMs) have enabled conversational systems with impressive performance in a variety of tasks, from code generation, to composing essays, to passing STEM and legal exams, to a new paradigm for knowledge search.
Konstantina Christakopoulou, Iris Qu, John Canny, Andrew Goodridge, Cj Adams, Minmin Chen, Maja J. Mataric   +6 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Gradient-Free De Novo Learning

Entropy
This technical note applies active inference to the problem of learning goal-directed behaviour from scratch, namely, de novo learning. By de novo learning, we mean discovering, directly from observations, the structure and parameters of a discrete ...
Karl Friston, Thomas Parr, Conor Heins, Lancelot Da Costa, Tommaso Salvatori, Alexander Tschantz, Magnus Koudahl, Toon Van de Maele, Christopher Buckley, Tim Verbelen   +9 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Estonian Road Network and Road Management

The Baltic Journal of Road and Bridge Engineering, 2006
Estonian public road network is one of the densest in the Baltic and Nordic countries with the 52,8 % of paved state roads. Also it is specific in the sense of the organisation of road management the maintenance of which is implemented partly by private ...
Andrus Aavik
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A scoping review of studies for senior nursing home planning in Japan—Trajectory of introducing private rooms and unit care system in nursing home

Japan Architectural Review
In aging and aged countries, one of the main issues is to establish sufficient nursing homes for seniors. Japan, as one of the most rapidly aged countries, has been reforming nursing homes for the elderly since the 1990s and established a long‐term care ...
Tatsuya Nishino, Haruka Tsukuda, Shigeki Matsubara, Satoshi Ishii, Yukiko Inoue, Hiroshi Tachibana, Kentaro Yamaguchi, Lai Sima, Ui Mimasaku   +8 more
doaj   +1 more source