Results 61 to 70 of about 3,211 (214)

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source

Congenital heart defects genetic architecture in a small cohort: an integrated approach to prioritizing variants

Frontiers in Cardiovascular Medicine
IntroductionCongenital heart defects (CHD) constitute a prevalent group of structural birth anomalies, characterised by substantial genetic heterogeneity and diverse clinical phenotypes.MethodsTo investigate the underlying genetic architecture, we ...
Anna V. Korobeinikova, Ekaterina S. Petriaikina, Dmitry I. Tychinin, Vladimir S. Yudin, Naida I. Bulaeva, Sayaly M. Gyulmamedova, Georgy A. Khugaev, Tatiana V. Sukhacheva, Ekaterina A. Snigir, Sergey I. Mitrofanov, Antonina M. Rumyantseva, Dmitry V. Svetlichnyy, Sergey M. Yudin, Elena Z. Golukhova, Veronika I. Skvortsova   +14 more
doaj   +1 more source

On The Bureaucrats'Behavior in Public Planning Agency

INFRASTRUCTURE PLANNING REVIEW, 1998
Existing studies on the bureaucracy have not dealt with organization structure or transmission of information clearly. In this paper we build a model for the Bureaucrats' Behavior on the basisof game theory. We focus on Herd Behavior of bureaucrats which depends on the probability of their ability or transmission of information change, bureaucrats ...
OKADA, Masami, UEDA, Takayuki, TAGAWA, Yoshitaka   +2 more
openaire   +2 more sources

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

GWAS shows links between EDARADD and LRFN5 and performance in professional athletes

BMC Sports Science, Medicine and Rehabilitation
Background Research into genetic markers associated with sports performance and aerobic capacity has been gaining momentum. However, despite the discovery of numerous molecular and genetic markers, there is still a gap in understanding the variations in ...
M. V. Terekhov, R. V. Deev, A. I. Kadykova, I. H. Dzhumaniiazova, A. A. Mamchur, E. A. Zelenova, L. R. Matkava, M. V. Ivanov, D. A. Kashtanova, S. I. Mitrofanov, L. A. Golubnikova, A. I. Nekrasova, I. G. Kalashnikova, A. A. Ivashechkin, V. V. Maksyutina, O. V. Varlamova, V. S. Yudin, A. A. Keskinov, A. V. Zholinsky, S. A. Kraevoy, S. M. Yudin, V. I. Skvortsova   +21 more
doaj   +1 more source

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

Frontiers in Immunology
COVID-19 is characterized by systemic pro-inflammatory shifts with the development of serious alterations in the functioning of the immune system. Investigations of the gene expression changes accompanying the infection state provide insight into the ...
Vasiliy E. Akimov, Dmitriy I. Tychinin, Olga A. Antonova, Abusaid M. Shaymardanov, Maria D. Voronina, Kseniia A. Deinichenko, Oleg D. Fateev, Vladimir S. Yudin, Sergey M. Yudin, Vladimir E. Mukhin, Svetlana V. Romanova, Aleksandra I. Nekrasova, Anastasia S. Zhdanova, Anastasia V. Tsypkina, Ivan S. Vladimirov, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +20 more
doaj   +1 more source