Results 51 to 60 of about 193,723 (309)

Analysis of HERV-K (HML2) Expression in Colorectal Cancer Samples

Epigenomes
Background: HML-2 subgroup mobile genetic elements of the HERV-K family were described to participate in carcinogenesis processes, but their expression and epigenetic regulation in molecular subtypes of colorectal cancer (CRC) remain partly characterized.
Valentina S. Obrezanenko, Polina M. Shulga, Anastasia G. Volkova, Anastasia A. Primova, Yulia A. Remizova, Ivan O. Meshkov, Alexandra D. Kikot, Daria A. Tarasova, Ekaterina S. Bolashova, Alexey A. Ivashechkin, Antonida V. Makhotenko, Ekaterina A. Snigir, Yulia A. Masyukova, Elizaveta I. Radion, Olesya A. Kuznetsova, Maria S. Cheporova, Michail Y. Fedyanin, Alexey A. Tryakin, Valentin V. Makarov, Vladimir S. Yudin, Anton A. Keskinov, Anna S. Makarova   +21 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Triple Combinations of AAV9-Vectors Encoding Anti-HIV bNAbs Provide Long-Term In Vivo Expression of Human IgG Effectively Neutralizing Pseudoviruses from HIV-1 Global Panel

Viruses
Anti-human immunodeficiency virus (HIV) broadly neutralizing antibodies (bNAbs) offer a promising approach for the treatment of HIV-1. The current paradigm for antibody therapy involves passive antibody transfer, requiring regular delivery of bNAbs in ...
German A. Shipulin, Dina V. Glazkova, Felix A. Urusov, Boris V. Belugin, Valeriya Dontsova, Alexandra V. Panova, Alyona A. Borisova, Galina M. Tsyganova, Elena V. Bogoslovskaya   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Multi-Role Collaboration of Ministries and Institutions in the Implementation of Agrarian Reform in Indonesia

BHUMI: Jurnal Agraria dan Pertanahan, 2020
Agrarian reform is a homework that will not be completed only with sectoral approach. The real agrarian reform is not just dividing and legalizing the land, but making the land parcels have better access.
Sigit Santosa, Arditya Wicaksono, Romi Nugroho   +2 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

An overview of evaluating the efficacy of microbial pathogens for biological control of the red palm weevil Rhynchophorus ferrugineus (Olivier, 1790) (Coleoptera: Curculionidae) insights from laboratory and field studies

Egyptian Journal of Biological Pest Control
Background This overview explores the use of entomopathogenic nematodes (EPNs), fungi (EPFs), bacteria (EPBs), and viruses (EPVs) as biological control strategies against the red palm weevil (RPW) (Rhynchophorus ferrugineus), a significant pest of date ...
Koko Dwi Sutanto, Catur Raharjo Febrayanto, Wiratno Wiratno, Dwinita Wikan Utami, Fitri Susiyanti, Mohammad Agus Yulianto, Araz Meilin, Iwa Mara Trisawa   +7 more
doaj   +1 more source

ANALYSIS OF RISK FACTORS AND THE IMPACT OF BULLYING BEHAVIOR ON ADOLESCENTS IN JUNIOR HIGH SCHOOLS IN GRESIK REGENCY

Jurnal Ilmiah Kesehatan
Bullying is a serious problem, as it can have a long-term impact on severe psychological problems, such as low self-esteem to deep depression, aggression, and school refusal which can lead to dropping out of school.
suyanto, Riski Dwi Prameswari, Havy Wardana, Tomi Indarto, Anik Nur Kholifah   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Geographic Patterns. Minnesota's Changing Agricultural Land.

, 1988
This 1988 report presents maps on everything from soil texture to cropland productivity to estimated land values per acre to conservation reserve lands.A joint effort of the Minnesota State Planning Agency and the Center for Urban and Regional Affairs ...
Minnesota State Planning Agency, CURA
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