Results 81 to 90 of about 1,625,954 (310)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

The Nature of Context-Sensitive Solutions, Stakeholder Involvement and Critical Issues in the Urban Context [PDF]

, 2011
Over the last several decades many transportation and planning agencies have experienced conflicting demands emerging from the need to develop projects in an expeditious manner while at the same time involving stakeholders in the decision-making process,
Botha, Jan, Panero, Marta
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

GWAS shows links between EDARADD and LRFN5 and performance in professional athletes

BMC Sports Science, Medicine and Rehabilitation
Background Research into genetic markers associated with sports performance and aerobic capacity has been gaining momentum. However, despite the discovery of numerous molecular and genetic markers, there is still a gap in understanding the variations in ...
M. V. Terekhov, R. V. Deev, A. I. Kadykova, I. H. Dzhumaniiazova, A. A. Mamchur, E. A. Zelenova, L. R. Matkava, M. V. Ivanov, D. A. Kashtanova, S. I. Mitrofanov, L. A. Golubnikova, A. I. Nekrasova, I. G. Kalashnikova, A. A. Ivashechkin, V. V. Maksyutina, O. V. Varlamova, V. S. Yudin, A. A. Keskinov, A. V. Zholinsky, S. A. Kraevoy, S. M. Yudin, V. I. Skvortsova   +21 more
doaj   +1 more source

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

Frontiers in Immunology
COVID-19 is characterized by systemic pro-inflammatory shifts with the development of serious alterations in the functioning of the immune system. Investigations of the gene expression changes accompanying the infection state provide insight into the ...
Vasiliy E. Akimov, Dmitriy I. Tychinin, Olga A. Antonova, Abusaid M. Shaymardanov, Maria D. Voronina, Kseniia A. Deinichenko, Oleg D. Fateev, Vladimir S. Yudin, Sergey M. Yudin, Vladimir E. Mukhin, Svetlana V. Romanova, Aleksandra I. Nekrasova, Anastasia S. Zhdanova, Anastasia V. Tsypkina, Ivan S. Vladimirov, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +20 more
doaj   +1 more source

The Challenges and Obstacles of Post-Disaster Road Infrastructure Reconstruction in the Pre-Construction Phase [PDF]

, 2015
Purpose The reconstruction of road infrastructure in the post-disaster context require different approach when compared with road projects in the normal development context.
Amaratunga, Dilanthi, Hayat, Ezri, Malalgoda, Chamindi   +2 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

THE NEED FOR MACROECONOMIC PLANNING IN THE REPUBLIC OF MACEDONIA – INSTITUTIONAL AND METHODOLOGICAL ASPECTS [PDF]

The system of indicative macroeconomic planning requires preparation and application of an adequate institutional, analytical, methodological and modeling framework in the Republic of Macedonia.
Sasho Kjosev
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Leveraging two novel droplet−based single−cell RNA Sequencing platforms: a comparative study with 10x genomics

BMC Genomics
Background Currently, single cell transcriptome profiling technology is gaining popularity, with an increasing number of novel platforms emerging. The development of new technologies is aimed at improving data quality, scale, cost, or labor intensity ...
A. V. Maluchenko, E. S. Avsievich, Ia. S. Zvorygina, Z. G. Antysheva, D. O. Maksimov, M. V. Boytsova, D. V. Tabakov, N. A. Bodunova, O. V. Glazova, D. I. Tychinin, A. V. Bolbat, E. S. Petriaikina, D. V. Svetlichnyy, S. M. Yudin, A. A. Keskinov, V. S. Yudin, M. V. Woroncow, V. I. Skvortsova, J. A. Krupinova, P. Yu Volchkov   +19 more
doaj   +1 more source