Results 91 to 100 of about 7,274,207 (297)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Oman Animal and Plant Genetic Resources Center’s (OAPGRC) Science Café: A Success Story” [PDF]

, 2017
Science Cafés are held in many towns and cities across the world for the promotion of scientific culture and the understanding of our daily lives, which we live in.
Hameed Challoob Ali Al-Khafaji, Al Saifi, Rasha Hilal, Nadiya Abubakr Al Saadi, Rasha Hilal Al Saifi, Ali Al-Khafaji, Hameed Challoob, Al Saadi, Nadiya Abubakr   +5 more
core   +2 more sources

Feeding ecology of the Red-and-green Macaw (Ara chloropterus; Gray 1859) in a habitat mosaic from Cerrado

Brazilian Journal of Biology
In the Brazilian Cerrado, the Red-and-green Macaw (Ara chloropterus) populations are facing an accelerated rate of habitat loss. Despite this, their feeding areas and primary food sources remain poorly understood.
J. Ragusa-Netto
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Editorial: Animal-Mediated Dispersal in Understudied Systems

Frontiers in Ecology and Evolution, 2020
Casper H. A. van Leeuwen, José L. Tella, Andy J. Green   +2 more
doaj   +1 more source

Bromélias e beija-flores: um modelo observacional para testar hipóteses sobre correlações e adaptações morfológicas recíprocas

Rodriguésia
Resumo Muitas angiospermas dependem da ação de animais para sua polinização. Embora a maioria das interações entre plantas e polinizadores não aparentem ser tão peculiares,de certa forma, parecem envolver algum grau de adaptação mútua de flor e animal. A
Liana Carneiro Capucho, Suely Dalcolmo, Tiago de Holanda Formigoni, Ary Gomes da Silva   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A comprehensive, multi-method dataset of plant-frugivore interactions in a Mediterranean hotspot

Scientific Data
Mutualistic plant-animal interactions for seed dispersal are crucial for vegetation dynamics, benefiting over half of the world’s plant species. Beyond the tropics, the Mediterranean biome harbors the highest proportion of species adapted to endozoochory,
Eva Moracho, Juan Miguel Arroyo, Blanca Arroyo-Correa, Gemma Calvo, Pablo Homet, Jorge Isla, Miguel Jácome-Flores, Irene Mendoza, Elena Quintero, Francisco Rodríguez-Sánchez, Pablo Villalva, Pedro Jordano   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source