Results 111 to 120 of about 597,981 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plant-based dietary orientation and body composition: a cross-sectional study

open access: yesDiscover Food
Background The growing need for a sustainable and personalised diet requires new tools to evaluate plant-based dietary orientation. Methods We developed a composite dietary score combining food preferences and weekly consumption frequency to quantify ...
Mauro Lombardo
doaj   +1 more source

Using the Pathogen-Host Interactions database (PHI-base) to investigate plant pathogen genomes and genes implicated in virulence

open access: yesFrontiers in Plant Science, 2015
New pathogen-host interaction mechanisms can be revealed by integrating mutant phenotype data with genetic information. PHI-base is a multi-species manually curated database combining peer-reviewed published phenotype data from plant and animal pathogens
Martin eUrban   +3 more
doaj   +1 more source

Industrial Grain Hemp Planting Date Trial [PDF]

open access: yes, 2017
Hemp is a non-psychoactive variety of cannabis sativa L. The crop is one of historical importance in the U.S. and reemerging in worldwide importance as manufacturers seek hemp as a renewable and sustainable resource for a wide variety of consumer and ...
Cummings, Erica   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Agrobiodiversity and Its Conservation in Nepal [PDF]

open access: yes, 2020
Nepal is a part of the world\u27s biodiversity hotspot and ranks the 49th in the world for biodiversity. Agrobiodiversity and its conservation status were studied through literature review, field survey, key informant survey and focus group discussion ...
Ghimire, K. H. (Krishna)   +8 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The interaction between dietary nitrates/nitrites intake and gut microbial metabolites on metabolic syndrome: a cross-sectional study

open access: yesFrontiers in Public Health
BackgroundMetabolic syndrome (MetS) prevalence has increased globally.The evidence shows thatdiet and gut microbial metabolites includingtrimethylamine N-oxide (TMAO) and kynurenine (KYN) play an important role in developing MetS.
Atieh Mirzababaei   +9 more
doaj   +1 more source

Technology and Biological Weapons: Future Threats [PDF]

open access: yes, 2004
Ye
Davison, N., Millett, P., Nixdorff, K.
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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