Results 121 to 130 of about 25,008,290 (299)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Quality Characteristics of Low-Fat Sausage Using Cultured Mushroom Mycelium

open access: yesFood Science of Animal Resources
This study compared the physicochemical properties of mushroom mycelium before and after rinsing, in addition to the physicochemical and textural properties of sausages with mushroom mycelium added at 0%, 25%, 50%, 75%, and 100% ratios.
Yu-Na Oh, Hack-Youn Kim
doaj   +1 more source

Costly, confusing, polarizing, and suspect: public perceptions of plant- based eating from a thematic analysis of social media comments

open access: yesFrontiers in Sustainable Food Systems
IntroductionA key approach to fostering more sustainable food systems involves shifting dietary patterns towards increased plant-based eating. However, plant-based eating remains low among Canadians.
Katherine F. Eckert   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A Comparative Study on Novel-Assisted Extraction Techniques for Retrieving Protein from Moringa oleifera Seeds

open access: yesFoods
Moringa oleifera seeds are rich in protein, yet their potential as plant-based protein in food remains underutilized. This study evaluated the extraction efficiency, composition, and techno-functional properties of moringa seed protein isolate (MSPI ...
Paul Ndubuisi Anyiam   +3 more
doaj   +1 more source

The Promise of Evidence-Based Policymaking: Appendices E-H

open access: yes, 2017
Supplementary appendices that support the final report of the Commission on Evidence-Based Policymaking including ..
United States. Commission on Evidence-Based Policymaking.
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Optimizing Postharvest Edible Coatings for Fruit and Vegetables with Plant-Based Polysaccharides

open access: yesFoods
Polysaccharide-based edible coatings are increasingly explored as sustainable strategies for maintaining quality of fresh produce, acting as barriers to gas exchange while improving mechanical and optical properties.
Marcos D. Ferreira   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Promise of Evidence-Based Policymaking

open access: yes, 2017
Report of the Commission on Evidence-Based Policymaking providing a final report of their findings that..
United States. Commission on Evidence-Based Policymaking.
core  

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