Results 71 to 80 of about 87,057 (261)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Potential of Bacillus sp. SNRUSA4 for Plant Growth Promotion and Biological Control Against Bacterial and Fusarium Wilt in Tomato [PDF]

Anais da Academia Brasileira de Ciências
Tomato cultivation worldwide faces problems with bacterial wilt and Fusarium wilt, which cause significant yield losses. This study evaluated Bacillus sp.
SUWAPHA SAWIPHAK, AROON WONGJIRATTHITI
doaj   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The genome of the endophytic bacterium H. frisingense GSF30T identifies diverse strategies in the Herbaspirillum genus to interact with plants

Frontiers in Microbiology, 2013
The diazotrophic, bacterial endophyte Herbaspirillum frisingense GSF30T has been identified in biomass grasses grown in temperate climate, including the highly nitrogen-efficient grass Miscanthus.
Daniel eStraub, Michael eRothballer, Anton eHartmann, Uwe eLudewig   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

OPCIONES DE MANEJO SOSTENIBLE DEL SUELO EN ZONAS ARIDAS: APROVECHAMIENTO DE LA HALÓFITA Salicornia bigelovii (Torr.) Y USO DE BIOFERTILIZANTES EN LA AGRICULTURA MODERNA

Tropical and Subtropical Agroecosystems, 2010
The study and development of plant resources in arid-saline environments is increasing. Salicornia bigelovii is a halophyte of great interest. However, the productivity of these plants is limited by nitrogen availability.
Edgar Omar Rueda Puente, F. Beltran, F. Ruiz, R. Valdez, J. Garcia, N. Avila, L. Partida, B. Murillo   +7 more
doaj  

Diazotrophic bacteria and nitrogen fertilization on the growth of micropropagated pineapple plantlets during acclimatization

Ciência Rural
: This study examines the effect of inoculation with diazotrophic bacteria and nitrogen fertilization on the growth of micropropagated pineapple cv. 'Vitória' plantlets during the acclimatization period.
Aurilena de Aviz Silva, Almy Junior Cordeiro de Carvalho, Flávia Paiva de Freitas, Patrícia Gomes de Oliveira Pessanha, Paulo Cesar dos Santos, Mírian Peixoto Soares da Silva, Tábatha de Souza Vasconcelos, Fábio Lopes Olivares   +7 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Determination of biotechnological potential of poultry litter isolated bacteria

Bioscience Journal
Poultry litter is composed of residues from industrial wood processing, serving as a bed for the animals. It has also been widely used as an agricultural biofertilizer, increasing its economic importance.
Renata Battisti, Adriana Junkerfuerbom, Kawana Nasser Machado, Dany Mesa, Marise Fonseca dos Santos, Eliane Cristina Gruszka Vendruscolo   +5 more
doaj   +1 more source

Biodiversity of Endorhizospheric Plant Growth Promoting Bacteria [PDF]

Journal of Biodiversity, Bioprospecting and Development, 2014
Endorhizospheric bacteria also known as endophytic bacteria that resides within living plant tissues without substantially harming plants have found a large number of applications in today’s agriculture such as nutrient cycling, tolerance to biotic and abiotic stress as well as promotion of plant growth.
openaire   +1 more source