Results 101 to 110 of about 2,977,871 (300)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The physiology of flowering in the Australian paper daisies Helipterum roseum and Helichrysum bracteatum [PDF]
, 1989 Thesis (Ph.D.) -- University of Adelaide, Dept.
Sharman, Kerry Veianne
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Kingdom-wide comparison reveals the evolution of diurnal gene expression in Archaeplastida
Nature Communications, 2019 The diurnal cycle exerts influences on various aspects of plant biology. Here, the authors generate and compare diurnal transcriptomics data from nine members of Archaeplastida representing major clades.
Camilla Ferrari +11 more
doaj +1 more source
HEXOKINASE 1 is required for glucose-induced repression of bZIP63, At5g22920 and BT2 in Arabidopsis
Frontiers in Plant Science, 2015 Simple sugars, like glucose and sucrose, act as signals to modulate the expression of hundreds of genes in plants. Frequently, however, it remains unclear whether this regulation is induced by the sugars themselves or by their derivatives generated in ...
Sabine eKunz +3 more
doaj +1 more source
, 2014 The cerrado is the most extensive savanna ecosystem of South America and a biodiversity hotspot, harboring a diverse flora ([7,000 species) with high levels of endemism. More than 50 % of the cerrado's approximately 2 million km 2 has been converted into
Ramos Silva, Lucas de Carvalho +4 more
core +1 more source
The Role of Bundle Sheath Extensions and Life Form in Stomatal Responses to Leaf Water Status [PDF]
, 2011 Published by and copyright by American Society of Plant Biologists. Refer to definitive publisher's version for full text of article: http://www.plantphysiol.org/content/156/2/962Bundle sheath extensions (BSEs) are key features of leaf structure with ...
Buckley, Thomas N. +5 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Shedding Light on Large-Scale Chromatin Reorganization in Arabidopsis thaliana [PDF]
, 2012 Plants need to respond quickly and appropriately to various types of light signals from the environment to optimize growth and development. The immediate response to shading, reduced photon flux (low light), and changes in spectral quality involves ...
van Zanten, M. +7 more
core +1 more source