MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Elevational Distribution Patterns and Driving Factors of Plant Carbon Storage Across Different Functional Groups in Subalpine Grasslands of the Eastern Loess Plateau, China. [PDF]
Plants (Basel)Xu M, Wang J, Wei K, Yu X, Huo N.
europepmc +1 more source
First steps towards distinguishing Mediterranean vegetation root marks on bones: An experimental approach. [PDF]
PLoS OneMacho-Callejo A +4 more
europepmc +1 more source
Fungal symbiosis alters non-host, community-level plant trait response to N enrichment in a low-nutrient sand dune system. [PDF]
OecologiaWalker SL, Emery SM.
europepmc +1 more source
Mechanisms of Pseudomonas spp. as plant growth promoting rhizobacteria: plant nutrition and biocontrol. [PDF]
Antonie Van LeeuwenhoekSatognon F, Akuku V.
europepmc +1 more source
Correction to: S-RNase-based self-incompatibility in angiosperms: Degradation, condensation, and evolution. [PDF]
Plant Physioleuropepmc +1 more source
Castilleja : the newsletter of the Wyoming Native Plant Society
, 1994 Wyoming Native Plant Society.
core