Results 91 to 100 of about 2,909,796 (290)

Constructionist Learning in Anatomy Education: What Anatomy Students Can Learn through Serious Games Development [PDF]

open access: yes, 2012
In this paper we describe the use of 3D games technology in human anatomy education based on our MSc in Medical Visualisation and Human Anatomy teaching practice, i.e.
Kim Bale   +8 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The First Textbook of Anatomy in Korea

open access: yes, 2006
The first hospital to practice western medicine in Korea, Chejungwon (제중원), was opened on April 10, 1885. Then on March 29, 1886, Chejungwon Medical School, Korea’s first school to teach western medicine, opened.
박형우
core  

Occurrence and structure of extrafloral nectariesin Pterodon pubescens Benth. and Pterodon polygalaeflorus Benth.

open access: yesPesquisa Agropecuária Brasileira, 2001
Extrafloral nectaries (EFNs) are structurally variable and widely spread among the angiosperms. The occurrence of EFNs in leaves of Pterodon polygalaeflorus Benth. and Pterodon pubescens Benth. (Fabaceae: Papilionoideae) were detected in adult specimens,
Paiva Élder Antônio Sousa e   +4 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Plant Cell Structure & Metabolism/Anatomy/Plant Kingdom and Ecology: BIO 111

open access: yes, 2011
Plant Cell Structure & Metabolism/Anatomy/Plant Kingdom and Ecology: BIO 111, examination June ...
Buwa, L, Mayekiso, B
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Formação de raízes em estacas de duas espécies de Calliandra (Leguminosae - Mimosoideae)

open access: yesRodriguésia
RESUMO Calliandra brevipes e Calliandra tweedii, também conhecidas como caliandra ou esponjinha, são espécies nativas do Brasil cultivadas como plantas ornamentais. O objetivo deste trabalho foi avaliar os efeitos da aplicação de diferentes concentrações
Juliana Lischka Sampaio Mayer   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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