Results 171 to 180 of about 229,059 (307)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Root stomata in <i>Conium maculatum</i> (Apiaceae): anatomically verified occurrence and a comparative survey across Apioideae. [PDF]
Khazaei Z +4 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The sleeping giant needs coffee: Overlooked areas for integrating plant ecophysiology and evolutionary biology. [PDF]
Branch HA.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
An illustrated guide to dissection and abdominal anatomy of the yellow mealworm beetle. [PDF]
Rosa-Teijeiro C +2 more
europepmc +1 more source
The plant ontology as a tool for comparative plant anatomy and genomic analyses. [PDF]
Cooper L +21 more
europepmc +1 more source

