Results 81 to 90 of about 119,972 (263)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Editorial: Plant architecture: structure, development, evolution, and molecular/genetic regulation

Frontiers in Plant Science, 2023
Abelardo Carlos Vegetti
doaj   +1 more source

Synergistic Regulation of Planting Density and Mepiquat Chloride on Yield and Plant Architecture of Short-Season Cotton in the Yangtze River Basin, China

Agronomy
Optimizing planting density and mepiquat chloride (MC) is essential for simplified, machine-harvestable cotton production in the Yangtze River Basin. A two-year field experiment was conducted to explore the synergistic regulatory mechanisms of MC and ...
Yeling Qin, Zhangshu Xie, Fang Cheng, Lijuan Zheng, Youhong Jiang, Xiaoju Tu, Aiyu Liu, Zhonghua Zhou   +7 more
doaj   +1 more source

Representing and encoding plant architecture: A review [PDF]

Annals of Forest Science, 2000
A plant is made up of components of various types and shapes. The geometrical and topological organisation of these components defines the plant architecture. Before the early 1970's, botanical drawings were the only means to represent plant architecture.
openaire   +5 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Mapping QTL for Plant Architecture-Related Traits in Soybean Across Multiple Environments

Plants
Improving soybean plant architecture is critical for enhancing yield potential. To dissect the genetics of related traits, a recombinant inbred line population of 175 F9:12 families (derived from Glycine max cultivars Jidou 12 [female] × Ji NF58 [male ...
Tao Wang, Qiang Chen, Xu Wang, Long Yan, Xiao-Lei Shi, Xiao-Dong Tang, Xiao-Tong Lei, Fu-Ming Xiao, Meng-Chen Zhang   +8 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Agronomic and Physiological Aspects of Programmed Cycle Pruning in Coffea arabica

Plants
Programmed Cycle Pruning (PCP) in Arabica coffee can positively influence plant physiology by modifying plant architecture, promoting a more uniform distribution of branches and leaves, and altering microclimatic conditions within the canopy ...
Diego Corona Baitelle, Sílvio de Jesus Freitas, Henrique Duarte Vieira, Abraão Carlos Verdin Filho, Sávio da Silva Berilli, Ismael Lourenço de Jesus Freitas, Weverton Pereira Rodrigues, Danilo Força Baroni, Silvério de Paiva Freitas, Guilherme Bessa Miranda, Stella Arndt, Orlando Carlos Huertas Tavares, Leandro Pin Dalvi, Paulo Cesar dos Santos   +13 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source