Results 51 to 60 of about 245,808 (313)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

open access: yesAdvanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam   +5 more
wiley   +1 more source

Chromatographic Separation of Breynia retusa (Dennst.) Alston Bark, Fruit and Leaf Constituents from Bioactive Extracts

open access: yesMolecules, 2020
Breynia retusa (Dennst.) Alston (also known as Cup Saucer plant) is a food plant with wide applications in traditional medicine, particularly in Ayurveda.
Stefano Dall’Acqua   +8 more
doaj   +1 more source

Elucidating Therapeutic and Biological Potential of Berberis baluchistanica Ahrendt Bark, Leaf, and Root Extracts

open access: yesFrontiers in Microbiology, 2022
Berberis baluchistanica Ahrendt is a medicinal plant known to have potential for the treatment of various diseases. In the present study, the ethanolic extracts of the bark, leaves, and roots of B.
Zareen Gul   +3 more
doaj   +1 more source

Fungal community survey of Fraxinus excelior in New Zealand [PDF]

open access: yes, 2012
The European Ash tree (Fraxinus excelsior) is widely grown throughout Europe. As a large deciduous tree species, it grows a tall, domed crown and has an attractive tree shape, so it is considered as a popular amenity tree species. European Ash is planted
Chen, Jie
core   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang   +8 more
wiley   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

open access: yes, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza   +374 more
core   +4 more sources

Crushed bark as a novel soil conditioner for organic plant production

open access: yesItalian Journal of Agronomy, 2021
Due to the reduction of cattle farming, the Finnish agricultural sector currently needs solutions to replace animal manure with new sustainable alternatives. This problem is especially acute for organic farms, which need livestock manure to improve soil fertility and soil organic carbon (SOC) to sustain yield.
Nurmi, Elina   +7 more
openaire   +4 more sources

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

ICP_OES determination of essential, trace essential, and non-essential elements in the anatomical parts of medicinal herb (Pentas Schimperiana) grown in Wolaita Zone, Ethiopia

open access: yesJournal of Agriculture and Food Research, 2023
This study aimed to evaluate the distribution of heavy metals (essential, trace essential, and non-essential) in medicinal herb (Pentas Schimperiana) roots, stem bark, and leaf samples collected from different geographical locations.
Tsegaye Bojago Dado   +4 more
doaj   +1 more source

Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]

open access: yes, 2019
Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
core   +1 more source

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