Results 281 to 290 of about 6,054,169 (340)

Notes on the Biology of Thyanta claceala (Hemiptera: Pentatomidae) on Tephrosia virginiana (Leguminosae), a New Host Plant [PDF]

, 1988
Barton, Harvey E., Harp, Phoebe A.
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

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Biosynthesis and Regulatory Mechanisms of Bioactive Compounds in Salvia miltiorrhiza, a Model System for Medicinal Plant Biology

Critical reviews in plant sciences, 2021
Salvia miltiorrhiza is one of the most well known species in the genus Salvia of the Lamiaceae with great economic, academic and medicinal value. It was recorded as a traditional Chinese medicine material first in about the second century BC and later in
Shanfa Lu
semanticscholar   +1 more source

An Introduction to Plant Biology

, 2022
Now, we come to offer you the right catalogues of book to open. an introduction to plant biology is one of the literary work in this world in suitable to be reading material.
D. Braungart, R. Arnett
semanticscholar   +1 more source

Unsupervised and semi-supervised learning: the next frontier in machine learning for plant systems biology.

The Plant Journal, 2022
The advancement of high-throughput omics technologies is leading plant biology research into the era of Big Data. Machine learning (ML) performs an important role in plant systems biology owing to its excellent performance and wide application in Big ...
Jun Yan, Xiangfeng Wang
semanticscholar   +1 more source

Insect Plant Biology

2005
Abstract Half of all insect species are dependent on living plant tissues, consuming about 10% of plant annual production in natural habitats and an even greater percentage in agricultural systems, despite sophisticated control measures.
Schoonhoven, L.M., van Loon, J.J.A., Dicke, M.   +2 more
openaire   +2 more sources

Large Language Models in Plant Biology

Trends in Plant Science
Large language models (LLMs), such as ChatGPT, have taken the world by storm. However, LLMs are not limited to human language and can be used to analyze sequential data, such as DNA, protein, and gene expression.
H. Lam, Xing Er Ong, Marek Mutwil
semanticscholar   +1 more source