Results 51 to 60 of about 3,000,917 (301)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A theoretical and practical analysis of the optimum breeding system for perennial ryegrass [PDF]

, 2011
peer-reviewedThe goal of plant breeding is to effectively and efficiently select for the best phenotypes leading to the development of improved cultivars. The objectives for this review are to describe and critically evaluate breeding methods appropriate
Conaghan, Patrick, Casler, M.D.
core   +1 more source

The sugar transporter SWEET10 acts downstream of FLOWERING LOCUS T during floral transition of Arabidopsis thaliana

BMC Plant Biology, 2020
Background Floral transition initiates reproductive development of plants and occurs in response to environmental and endogenous signals. In Arabidopsis thaliana, this process is accelerated by several environmental cues, including exposure to long days.
Fernando Andrés, Atsuko Kinoshita, Naveen Kalluri, Virginia Fernández, Vítor S. Falavigna, Tiago M. D. Cruz, Seonghoe Jang, Yasutaka Chiba, Mitsunori Seo, Tabea Mettler-Altmann, Bruno Huettel, George Coupland   +11 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Data integration for decision making in wheat breeding [PDF]

, 2011
Plant breeding is a production process requiring the creation of germplasm through taking existing successful cultivars and crossing them with new parental lines with agronomic and quality attributes of interest.
Diepeveen, Dean
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Shade Avoidance Restricts Soybean Breeding Progress and Increases Herbivore Susceptibility

Evolutionary Applications
High planting densities expose field crops to competition for light, which typically induces shade avoidance responses such as stem elongation. While adaptive in natural environments, these responses can lower yield and increase susceptibility to stress ...
Lukas Vonmetz, Emanuel B. Kopp, Simon Jäggi, Pascal A. Niklaus, Samuel E. Wuest   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Advances in plant gene-targeted and functional markers: a review [PDF]

, 2013
Public genomic databases have provided new directions for molecular marker development and initiated a shift in the types of PCR-based techniques commonly used in plant science.
Ildikó Varga, Poczai, Péter, Neil Bell, Hyvönen Jaakko, Valkonen, Jari PT, Maarja Laos, Hyvönen, Jaakko, Cseh, András, Varga Ildikó, Varga, Ildikó, Laos, Maarja, Cseh András, Bell Neil, Poczai Péter, Valkonen, Jari, Cseh, András Attila, Péter Poczai, Jari PT Valkonen, Valkonen Jari PT, Jaakko Hyvönen, Bell, Neil, András Cseh, Laos Maarja   +22 more
core   +1 more source