Results 151 to 160 of about 1,716,927 (360)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Modeling suction of unsaturated granular soil treated with biochar in plant microbial fuel cell bioelectricity system [PDF]

Kennedy C. Onyelowe, Ahmed M. Ebid, R. Jiménez, Viroon Kamchoom‬, M. Vishnupriyan, A. Arunachalam   +5 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Decoding self-recovery: Initial observations of radiofrequency stress responses in Nicotiana benthamiana

Plant Stress
This study investigates the cellular and molecular responses of Nicotiana benthamiana to radiofrequency (RF) exposure using a custom-built electrode–water bath system.
Won Kyong Cho, Young Soon Kim, Sunmee Choi, Gi Seok Kwon, Suk Hyun Kwon, Hyo Hyun Seo, Jeong Hun Lee, Sang Hyun Moh   +7 more
doaj   +1 more source

Thermoelectric cells cogeneration from biomass power plant: literature review [PDF]

, 2015
Augusto Bianchini, Filippo Donini, Marco Pellegrini   +2 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Mechanisms and kinetics of cellulose fermentation for protein production [PDF]

The development of a process (and ancillary processing and analytical techniques) to produce bacterial single-cell protein of good nutritional quality from waste cellulose is discussed.
Dunlap, C. A.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

AP1 is a pioneer transcription factor that programmes cell fate through MADS-domain protein tetramerisation

Genome Biology
Background In animals, pioneer transcription factors (TFs) have long been known to be crucial molecular players in programming cell fate. However, in plants much less is known about this functional class of TFs and how they mechanistically alter local ...
Xiaocai Xu, Manuel Neumann, Frederic Carew, Peilin Chen, Caroline Braeuning, Chloe Zubieta, Jose M. Muino, Cezary Smaczniak, Kerstin Kaufmann   +8 more
doaj   +1 more source