Results 271 to 280 of about 1,716,927 (360)

Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties. [PDF]

Front Plant Sci
Gallemí M, Montesinos JC, Zarevski N, Pribyl J, Skládal P, Hannezo E, Benková E.   +6 more
europepmc   +1 more source

Screening of north-east Mexico medicinal plants with activities against herpes simplex virus and human cancer cell line

, 2018
David A. Silva-Mares, Verónica M. Rivas-Galindo, Ricardo Salazar‐Aranda, Luis Alejandro Pérez-López, Noemí Waksman de Torres, Jonathan Pérez-Meseguer, Ernesto Torres-López   +6 more
openalex   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Teredinibacter turnerae secretome highlights key enzymes for plant cell wall degradation. [PDF]

Bioresour Bioprocess
De Guzman LIP, Carpina RC, Chua JCA, Yu ET.   +3 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Understanding pectin cross-linking in plant cell walls. [PDF]

Commun Biol
Obomighie I, Prentice IJ, Lewin-Jones P, Bachtiger F, Ramsay N, Kishi-Itakura C, Goldberg MW, Hawkins TJ, Sprittles JE, Knight H, Sosso GC.   +10 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A plant cell-based platform for the expression of complex proteins with fucose-reduced sialylated N-glycans. [PDF]

Plant Biotechnol J
Dianatkhah S, Kogelmann B, Melnik S, Eminger F, Kallolimath S, Sun L, Sumesgutner D, Traxlmayr MW, Sack M, Stoger E, Steinkellner H.   +10 more
europepmc   +1 more source

Cancer Patient Life Quality Improvement by T-Cell Stimulation with Five Edible Plants

Pichaet Wiriyachitra, Preeya Leelahagul, Sirithip Wiriyachitra, Ampai Panthong, Sakda Sreesangkom   +4 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source