Results 111 to 120 of about 437,892 (307)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Induction of PR-1 Proteins and Potentiation of Pathogen Signals by Salicylic Acid Exhibit the Same Dose Response and Structural Specificity in Plant Cell Cultures

open access: yesMolecular Plant-Microbe Interactions, 1998
Based on the marked difference in both dose response and structural specificity, it has been recently proposed that the induction of acquired resistance and pathogenesis-related (PR) proteins in intact plant leaves and the potentiation of pathogen ...
Zhixin Xie, Baofang Fan, Zhixiang Chen
doaj   +1 more source

Recombinant Expression of Archaeal Superoxide Dismutases in Plant Cell Cultures: A Sustainable Solution with Potential Application in the Food Industry. [PDF]

open access: yesAntioxidants (Basel), 2022
Gogliettino M   +10 more
europepmc   +1 more source

Plant Cell Culture System.

open access: yesKAGAKU KOGAKU RONBUNSHU, 1999
植物培養細胞を用いて有用二次代謝産物を生産したり, 有用な植物体を再生することは注目されている.ここでは, 植物細胞培養システムの応用研究の最近の成果を著者らの研究を含めて紹介する.二次代謝産物の生産においてカルス細胞培養による方法につき二段培養法, コンディショニング因子の効果を示し, 反応モデル, 細胞の固定化およびリアクターについて紹介を行った.毛状根による物質生産も, 根で作られる物質の生産には有効である.また, 植物体の再生は食糧や環境の問題解決に寄与すると考えられる.不定胚の生産やマイクロカプセル化による人工種子についての研究成果も記した.
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Bacterial Nanocellulose Fortified with Antimicrobial and Anti-Inflammatory Natural Products from Chelidonium majus Plant Cell Cultures. [PDF]

open access: yesMaterials (Basel), 2021
Zielińska S   +13 more
europepmc   +1 more source

High efficiency protoplast isolation from in vitro cultures and hairy roots of Maesa lanceolata [PDF]

open access: yes, 2010
In vitro cultures of the medicinal plant Maesa lanceolata were established to enable the cultivation of plant material for the production of protoplasts.
Geelen, Danny, Lambert, Ellen
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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