Results 231 to 240 of about 437,892 (307)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Risk assessment of plant-to-bacterium transgene flow associated with novel small synthetic genome (minisynplastome) platforms for plastid genetic engineering. [PDF]

FEMS Microbiol Ecol
Vincent AG, Fuentes Quispe IA, Majdi M, Dice LT, Harbison SA, Lenaghan SC, DeBruyn JM, Occhialini A.   +7 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Quorum-quenching halotolerant bacteria as biocontrol agents against potato phytopathogens. [PDF]

Sci Rep
Sánchez P, Monzón-Ramos A, Sampedro I, Llamas I, Palma F.   +4 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Amaryllidaceae Alkaloids and Phenolic Acids Identification in Leucojum aestivum L. Plant Cultures Exposed to Different Temperature Conditions. [PDF]

Molecules
Ptak A, Warchoł M, Morańska E, Laurain-Mattar D, Spina R, Dupire F, Waligórski P, Simlat M.   +7 more
europepmc   +1 more source

A new 13-lipoxygenase from Taxus media callus is functionally linked to paclitaxel biosynthesis. [PDF]

Sci Rep
Hanano A, Rahman F, Murphy D.
europepmc   +1 more source

Changes in Cell Aggregation in <i>Arabidopsis thaliana</i> Suspension Culture Following Knockout of GAUT Gene Family Members. [PDF]

Plants (Basel)
Frankevich TA, Permyakova NV, Sidorchuk YV, Deineko EV.   +3 more
europepmc   +1 more source

Editorial: Plant immune responses, evolutionary dynamics, control and transmission of plant ssDNA viruses, volume II. [PDF]

Front Plant Sci
Ascencio-Ibáñez JT, Rivera-Bustamante RF, Krenz B.   +2 more
europepmc   +1 more source