Results 141 to 150 of about 578,678 (215)

FE-SEM visualization of cortical microtubules in plant cells using freeze-fracture techniques. [PDF]

Plant Methods
Hatano T, Nakaba S, Nagata H, Doi I, Horikawa Y, Kimura S, Funada R.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fluorescence staining of the nucleus in living plant cells using dimidium bromide. [PDF]

Plant Biotechnol (Tokyo)
Ichikawa S, Kitamura M, Kodama Y.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues. [PDF]

New Phytol
Perri M, Khan MS, Wallabregue ALD, Voloboeva V, Ridgway AM, Smith EN, Bolland H, Hammond EM, Conway SJ, Weits DA, Flashman E.   +10 more
europepmc   +2 more sources

Single-cell metabolome and RNA-seq multiplexing on single plant cells. [PDF]

Proc Natl Acad Sci U S A
Kang M, Vu AH, Casper AL, Kim R, Wurlitzer J, Heinicke S, Yeroslaviz A, Caputi L, O'Connor SE.   +8 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Revealing plasma membrane protein dynamics in living plant cells with single-molecule tracking. [PDF]

J Exp Bot
Zur Oven-Krockhaus S, Rohr L, Rausch L, Harter K.   +3 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Exosome-like Nanoparticles Extracted from Plant Cells for Diabetes Therapy. [PDF]

Int J Mol Sci
Xiao X, Guo Y, Msomi NZ, Islam MS, Chu M.   +4 more
europepmc   +1 more source